Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384644 | 0.94 | PPARG (0.57) | PPARGCYP1A2PPARAEPHX2HPGD | |
| SCHEMBL19502669 | 0.89 | CYP1A2 (0.57) | PPARGCYP1A2PPARAEPHX2NR4A2 | |
| SCHEMBL27304316 | 0.86 | PPARG (0.50) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL11983359 | 0.86 | PPARG (0.50) | PPARGPPARAEPHX2HPGDALDH1A1 | |
| SCHEMBL7273958 | 0.86 | PPARG (0.50) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL9419783 | 0.84 | PPARG (0.49) | PPARGPPARAEPHX2HPGDALDH1A1 | |
| SCHEMBL7299030 | 0.84 | CPA1 (0.61) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL28005647 | 0.83 | PPARG (0.54) | PPARGPPARAHPGDALDH1A1CTBP2 | |
| O-Xylene SCHEMBL29008699 | 0.83 | CYP1A2 (0.54) | PPARGCYP1A2ALDH1A1NR4A2 | |
| SCHEMBL13857860 | 0.82 | PPARG (0.50) | PPARGCYP1A2PPARAEPHX2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5329033-A | Metallocene catalyst, indene containing ligands, alumoxane cocatalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| US-5278264-A | Catalytic polymerizing in presence of a transition metal metallocene | HOECHST AG (DE) | 1994-01-11 | — | — | US | disclosed |