Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076149 | 0.91 | CYP1A2 (0.36) | GRM8CYP1A2GRM7EGFR | |
| SCHEMBL1074296 | 0.90 | GRM1 (0.40) | PDE4BPDE4DGRM1GRM8CYP1A2 | |
| SCHEMBL1073998 | 0.89 | PDE4B (0.38) | PDE4BPDE4DGRM1CYP11B2EGFR | |
| SCHEMBL1074420 | 0.89 | CYP1A2 (0.38) | PDE4BPDE4DGRM8CYP1A2GRM7 | |
| SCHEMBL1076597 | 0.88 | ALDH1A1 (0.36) | GRM8CYP1A2GRM7EGFR | |
| SCHEMBL1075011 | 0.88 | GLA (0.40) | GRM8CYP1A2GRM7EGFR | |
| SCHEMBL1225373 | 0.87 | PDE4B (0.40) | PDE4BPDE4DGRM1CYP11B2AOC3 | |
| SCHEMBL1073034 | 0.84 | CYP1A2 (0.34) | GRM8CYP1A2GRM7 | |
| SCHEMBL1225303 | 0.84 | CYP1A2 (0.37) | GRM8CYP1A2GRM7P2RX7 | |
| SCHEMBL1074801 | 0.84 | CYP1A2 (0.40) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110045101-A1 | FUNGICIDAL SUBSTITUTED AZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-24 | — | — | US | claimed |
| EP-2274284-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. Du Pont de Nemours and Company (US) | 2011-01-19 | — | — | EP | claimed |
| WO-2009137538-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-12 | — | — | WO | claimed |
| WO-2009137651-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-12 | — | — | WO | claimed |
| US-20110045101-A1 | FUNGICIDAL SUBSTITUTED AZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-24 | — | — | US | disclosed |
| EP-2274284-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. Du Pont de Nemours and Company (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009137538-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009137651-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045101-A1 | FUNGICIDAL SUBSTITUTED AZOLES | CBR3, NOX3, CBR1 | PDE4B 784/4885PDE4D 1386/4885GRM1 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.