Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.71 |
| ▸ | DRD3 | P35462 | 17/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.69 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347379 | 0.90 | DRD2 (0.66) | DRD2DRD3KCNH2HTR2ADRD4 | |
| SCHEMBL9018457 | 0.84 | DRD2 (0.66) | DRD2DRD3KCNH2HTR2ADRD4 | |
| SCHEMBL6226262 | 0.84 | DRD2 (0.65) | DRD2DRD3KCNH2HTR2ADRD4 | |
| SCHEMBL7926486 | 0.83 | DRD2 (0.64) | DRD2DRD3KCNH2HTR2ADRD4 | |
| Imidoline SCHEMBL349290 | 0.83 | DRD2 (0.77) | DRD2DRD3KCNH2HTR2ADRD4 | |
| Imidoline SCHEMBL29555586 | 0.83 | DRD2 (0.77) | DRD2DRD3KCNH2HTR2ADRD4 | |
| SCHEMBL6220801 | 0.83 | DRD2 (0.68) | DRD2DRD3KCNH2HTR2ADRD4 | |
| Imidoline SCHEMBL122328 | 0.82 | DRD2 (0.75) | DRD2DRD3KCNH2HTR2ADRD4 | |
| Zetidoline SCHEMBL31664542 | 0.80 | DRD2 (0.73) | DRD2DRD3KCNH2HTR2ADRD4 | |
| Zetidoline SCHEMBL2111327 | 0.80 | DRD2 (0.73) | DRD2DRD3KCNH2HTR2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642351-A | TREATMENT OF OXAZOLIDINONE WITH ISOCYANATE OR ISOTHIOCYANATE | THE DOW CHEMICAL COMPANY (US) | 1987-02-10 | — | — | US | disclosed |