Zetidoline

Zetidoline

SCHEMBL31664542

CC1(C)CN(CCN2CCN(c3cccc(Cl)c3)C2=O)C1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 20/20 0.73
DRD3 P35462 20/20 0.73
KCNH2 Q12809 17/20 0.73
DRD4 P21917 1/20 0.68
HTR2A P28223 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zetidoline SCHEMBL2111327 1.00 DRD2 (0.73) DRD2DRD3KCNH2DRD4HTR2A
SCHEMBL11750239 0.86 DRD2 (0.67) DRD2DRD3KCNH2DRD4HTR2A
SCHEMBL11751503 0.85 DRD2 (0.66) DRD2DRD3KCNH2DRD4HTR2A
SCHEMBL11009753 0.84 DRD2 (0.56) DRD2DRD3KCNH2DRD4HTR2A
SCHEMBL11006287 0.82 DRD2 (0.54) DRD2DRD3KCNH2DRD4HTR2A
Hydrochloric Acid SCHEMBL11013155 0.81 DRD2 (0.53) DRD2DRD3KCNH2DRD4HTR2A
SCHEMBL11008516 0.80 DRD2 (0.52) DRD2DRD3KCNH2DRD4HTR2A
SCHEMBL10746212 0.80 DRD2 (0.71) DRD2DRD3KCNH2DRD4HTR2A
SCHEMBL11014135 0.80 DRD3 (0.52) DRD2DRD3KCNH2DRD4HTR2A
Imidoline SCHEMBL29555586 0.78 DRD2 (0.77) DRD2DRD3KCNH2DRD4HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250236679-A1 ANTI-DLL3 ANTIBODY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-24 US disclosed