Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 10/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | C1R | P00736 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10744226 | 0.93 | F12 (0.47) | F12PRSS1F2F10PLG | |
| SCHEMBL10745226 | 0.79 | F12 (0.58) | F12PRSS1F2F10PLG | |
| SCHEMBL10745469 | 0.78 | L3MBTL1 (0.46) | MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7285755 | 0.78 | PRSS1 (0.60) | F12PRSS1F2F10PLG | |
| Bromide SCHEMBL7289206 | 0.78 | PRSS1 (0.60) | F12PRSS1F2F10PLG | |
| SCHEMBL10851681 | 0.77 | PRSS1 (0.57) | F12PRSS1F2F10PLG | |
| SCHEMBL11043060 | 0.75 | KMT2A (0.68) | F12PRSS1F2F10PLG | |
| SCHEMBL31380450 | 0.75 | F12 (0.76) | F12PRSS1F2F10PLG | |
| SCHEMBL7337750 | 0.74 | F12 (0.71) | F12PRSS1F2F10PLG | |
| SCHEMBL10738968 | 0.74 | FTO (0.59) | F12PRSS1F2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634783-A | ENZYME INHIBITORS, ANTICOMPLEMENT AGENT | TORII & CO. LTD. (JP) | 1987-01-06 | — | — | US | disclosed |