Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668053 | 0.84 | KAT6A (0.52) | KAT6APDPK1CYP2A6LOXL2 | |
| SCHEMBL12658214 | 0.84 | KAT6A (0.52) | KAT6APDPK1CYP2A6LOXL2PIP4K2C | |
| Hydrochloric Acid SCHEMBL5692827 | 0.83 | KAT6A (0.51) | KAT6APDPK1CYP2A6LOXL2 | |
| Hydrochloric Acid SCHEMBL5692840 | 0.83 | KAT6A (0.51) | KAT6APDPK1CYP2A6LOXL2 | |
| SCHEMBL15805858 | 0.79 | PDPK1 (0.72) | KAT6APDPK1CYP2A6LOXL2PTGDR2 | |
| SCHEMBL21999853 | 0.78 | ACLY (0.50) | KAT6APDPK1CYP2A6LOXL2ACLY | |
| SCHEMBL16159287 | 0.76 | PDPK1 (0.67) | KAT6APDPK1CYP2A6LOXL2PTGDR2 | |
| SCHEMBL10408548 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL996104 | 0.75 | ALDH1A1 (0.48) | KAT6ACYP2A6ALDH1A1HSD17B10TDP1 | |
| SCHEMBL468088 | 0.75 | PDPK1 (0.60) | KAT6APDPK1CYP2A6LOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274296-A1 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS | Merck Sharp & Dohme Corp. (US) | 2011-01-19 | — | — | EP | disclosed |