Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378169 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2L3MBTL1KDM4EGAAHTT | |
| SCHEMBL19981514 | 0.83 | MAPT (0.50) | SMN1; SMN2L3MBTL1KDM4EGAAHTT | |
| SCHEMBL10755827 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1KDM4EGAAALDH1A1 | |
| SCHEMBL9051688 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1KDM4EGAAHTT | |
| SCHEMBL10753773 | 0.77 | MEN1 (0.41) | SMN1; SMN2L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL27737313 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1KDM4EMAPTNPC1 | |
| SCHEMBL29886718 | 0.74 | HPGD (0.58) | SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL10750236 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1KDM4EGAANPC1 | |
| SCHEMBL10748364 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1KDM4EGAAHTT | |
| SCHEMBL5235651 | 0.73 | FDPS (0.35) | SMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634704-A | HISTAMINE AND SEROTONINE ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1987-01-06 | — | — | US | disclosed |