Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749142 | 0.80 | NOTUM (0.38) | NOTUMIDO1KDM4E | |
| SCHEMBL10750583 | 0.77 | NPC1 (0.39) | NOTUMCNR2RAB9AIDO1NPC1 | |
| SCHEMBL1577055 | 0.76 | L3MBTL1 (0.32) | NOTUMRAB9AMAPK1NPC1 | |
| SCHEMBL12209197 | 0.74 | NOTUM (0.49) | NOTUMARCNR2RAB9AIDO1 | |
| SCHEMBL29678302 | 0.69 | TSHR (0.58) | NOTUMMAPK1IDO1SCN2AKDM1A | |
| SCHEMBL1263144 | 0.69 | TSHR (0.58) | NOTUMMAPK1IDO1SCN2AKDM1A | |
| SCHEMBL27518820 | 0.68 | NOTUM (0.40) | NOTUMARCNR2IDO1BRD4 | |
| Ammonia Solution, Strong SCHEMBL20472961 | 0.67 | MAOB (0.56) | NOTUMMAPK1IDO1SCN2AKDM1A | |
| SCHEMBL8482382 | 0.66 | NOTUM (0.36) | NOTUMRAB9AMAPK1KDM4EHSD17B10 | |
| SCHEMBL12890159 | 0.65 | DRD2 (0.40) | NOTUMIDO1KDM4EHSD17B10KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675044-A | DEFOLIANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-06-23 | — | — | US | disclosed |
| US-4569690-A | HERBICIDES, FUNGICIDES, PLANT DESSICANTS, DEFOLIANTS | UNIROYAL, INC. (US) | 1986-02-11 | — | — | US | disclosed |
| EP-0104940-A1 | 3-Aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides | UNIROYAL, INC. (US) | 1984-04-04 | — | — | EP | disclosed |