Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13228832 | 0.87 | BCL9 (0.55) | HPGDBCL9CTNNB1KMT2AALDH1A1 | |
| SCHEMBL27261307 | 0.85 | KMT2A (0.50) | HPGDKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL27667241 | 0.84 | HPGD (0.53) | HPGDKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL6943160 | 0.83 | KMT2A (0.50) | HPGDKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL4810160 | 0.83 | LMNA (0.62) | BCL9CTNNB1KMT2AALDH1A1GAA | |
| SCHEMBL13721468 | 0.82 | BCL9 (0.47) | HPGDBCL9CTNNB1KMT2AALDH1A1 | |
| SCHEMBL28245383 | 0.82 | HPGD (0.55) | HPGDKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL27339690 | 0.81 | HPGD (0.50) | HPGDKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL29268235 | 0.81 | ALDH1A1 (0.49) | BCL9CTNNB1KMT2AALDH1A1GAA | |
| SCHEMBL28468806 | 0.80 | BCL9 (0.49) | BCL9CTNNB1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102917683-B | Porous dissolvable solid substrate and surface resident coating comprising water sensitive active | THE PROCTER & GAMBLE CO. (US) | 2015-08-05 | — | — | CN | claimed |
| CN-102917683-A | Porous dissolvable solid substrate and surface resident coating comprising water sensitive active | PROCTER & GAMBLE | 2013-02-06 | — | — | CN | claimed |
| CN-102917683-B | Porous dissolvable solid substrate and surface resident coating comprising water sensitive active | THE PROCTER & GAMBLE CO. (US) | 2015-08-05 | — | — | CN | disclosed |
| CN-104540903-A | Irreversible thermochromic ink compositions | SANFORD LP | 2015-04-22 | — | — | CN | disclosed |
| CN-1309424-C | Fragrance dispensing device | GIVAUDAN SA (CH) | 2007-04-11 | — | — | CN | disclosed |
| CN-1713914-A | Novel drug for treating chronic obstructive pulmonary disease | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-12-28 | — | — | CN | disclosed |
| CN-1668342-A | Fragrance dispensing device | GIVAUDAN SA (CH) | 2005-09-14 | — | — | CN | disclosed |
| CN-1582166-A | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-02-16 | — | — | CN | disclosed |
| CN-1045260-A | Novel local narcotic compound and preparation method thereof | ASTRA AB (SE) | 1990-09-12 | — | — | CN | disclosed |
| US-4656310-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1987-04-07 | — | — | US | disclosed |
| US-4532355-A | Substituted triaryl phosphonium derivatives | HOFFMANN-LA ROCHE INC. (US) | 1985-07-30 | — | — | US | disclosed |
| US-4319048-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4224244-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4215215-A | 9-Phenyl-nonate traene compounds | HOFFMANN-LA ROCHE INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4105681-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-08-08 | — | — | US | disclosed |