SCHEMBL10749655

SCHEMBL10749655

NS(=O)(=O)c1ccccc1S(N)(=O)=O.[CaH2]

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 16/20 0.67
CA1 P00915 12/20 0.67
CA9 Q16790 12/20 0.67
CA12 O43570 7/20 0.67
CA6 P23280 4/20 0.67
CA5A P35218 4/20 0.67
CA7 P43166 4/20 0.67
CA4 P22748 3/20 0.67
CA5B Q9Y2D0 3/20 0.67
CA14 Q9ULX7 2/20 0.67
CYP2C9 P11712 1/20 0.67
CA3 P07451 1/20 0.52
PLA2G7 Q13093 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
LDHA P00338 1/20 0.50
CDK2 P24941 1/20 0.50
GAA P10253 1/20 0.48
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202947 0.97 CA2 (0.70) CA2CA1CA9CA12CA6
SCHEMBL10750176 0.94 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL10750170 0.94 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL9827202 0.84 CA2 (0.56) CA2CA1CA9CA12CA6
SCHEMBL391939 0.84 CA2 (0.56) CA2CA1CA9CA12CA6
SCHEMBL4648981 0.84 CA2 (0.56) CA2CA1CA9CA12CA6
SCHEMBL1080972 0.82 CA2 (0.61) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL5740459 0.82 CA2 (0.54) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL6754825 0.82 CA2 (0.54) CA2CA1CA9CA12CA6
SCHEMBL1808913 0.80 CA2 (0.58) CA2CA1CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4645527-A PLANT SAFENING AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-02-24 US disclosed