SCHEMBL9827202

SCHEMBL9827202

NS(=O)(=O)c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 14/20 0.56
CA1 P00915 11/20 0.56
CA9 Q16790 10/20 0.56
CA12 O43570 5/20 0.56
CA6 P23280 4/20 0.56
CA7 P43166 4/20 0.56
CA5A P35218 4/20 0.56
CA4 P22748 3/20 0.56
CA5B Q9Y2D0 3/20 0.56
CA14 Q9ULX7 2/20 0.56
CYP2C9 P11712 1/20 0.56
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA3 P07451 1/20 0.44
PLA2G7 Q13093 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
LDHA P00338 1/20 0.43
CDK2 P24941 1/20 0.43
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202947 0.87 CA2 (0.70) CA2CA1CA9CA12CA6
SCHEMBL250199 0.87 ALDH1A1 (0.55) CA2CA1CA9CA12CA6
SCHEMBL10750176 0.84 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL10750170 0.84 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL10749655 0.84 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL10415459 0.79 GAA (0.50) CA2CA1CA9CA12CA6
SCHEMBL29540971 0.75 CA1 (0.62) CA2CA1CA9CA12CA6
SCHEMBL8071 0.75 CA1 (0.62) CA2CA1CA9CA12CA6
SCHEMBL9360977 0.75 TDP1 (0.44) CA2CA1CA9CA12CA6
SCHEMBL30690139 0.75 ALDH1A1 (0.44) CA2CA1CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192489-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-04-10 EP disclosed
US-4956005-A PREEMERGENCE OR POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-11 US disclosed
US-4802906-A Herbicidal ortho-sulfonamide benzenesulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-07 US disclosed
US-4718938-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-12 US disclosed
US-4662932-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-05 US disclosed
US-4619688-A Herbicidal sulfonylguanidine derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-10-28 US disclosed
EP-0192489-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-27 EP disclosed
EP-0148498-A1 Sulfonylguanidine derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-07-17 EP disclosed
US-3996000-A USING THE EXHAUSTION PROCESS BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed