Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.37 |
| ▸ | ADH1A | P07327 | 4/20 | 0.37 |
| ▸ | ADH1C | P00326 | 3/20 | 0.34 |
| ▸ | ADH7 | P40394 | 2/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455122 | 0.74 | ADH1B (0.33) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19982848 | 0.69 | HTT (0.44) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL28190120 | 0.69 | — | — | |
| SCHEMBL28146046 | 0.69 | — | — | |
| SCHEMBL27840791 | 0.68 | — | — | |
| SCHEMBL21238479 | 0.65 | — | — | |
| SCHEMBL17376390 | 0.64 | — | — | |
| SCHEMBL26030016 | 0.64 | — | — | |
| SCHEMBL26275196 | 0.64 | ALDH1A1 (0.44) | — | |
| SCHEMBL6529137 | 0.64 | ADH1B (0.36) | ADH1BADH1AADH1CADH7ADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656263-A | 6-β-substituted penicillanic acid compound free of the 6-α-epimer | PFIZER INC. (US) | 1987-04-07 | — | — | US | disclosed |
| US-4518530-A | 6-β-Substituted penicillanic acids as β-lactamase inhibitors | PFIZER INC. (US) | 1985-05-21 | — | — | US | disclosed |
| US-4517126-A | Penicillanic acid derivative | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |