Biphenyl

Biphenyl

SCHEMBL10749847

C=CCOC(=O)CCCCC(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TSHR P16473 2/20 0.53
CYP3A4 P08684 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
CASP1 P29466 2/20 0.44
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
MGLL Q99685 2/20 0.42
HSD17B10 Q99714 1/20 0.42
LTB4R Q15722 3/20 0.42
MAPT P10636 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41
FFAR1 O14842 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87404 0.87 TSHR (0.67) PKMSMN1; SMN2TSHRALDH1A1GAA
SCHEMBL530482 0.85 TSHR (0.70) PKMSMN1; SMN2TSHRALDH1A1GAA
SCHEMBL2249400 0.85 TSHR (0.70) PKMSMN1; SMN2TSHRALDH1A1GAA
Ethylene SCHEMBL28109697 0.85 TSHR (0.65) PKMSMN1; SMN2TSHRALDH1A1GAA
SCHEMBL14533033 0.85 TSHR (0.70) PKMSMN1; SMN2TSHRALDH1A1GAA
SCHEMBL11763281 0.85 TSHR (0.70) PKMSMN1; SMN2TSHRALDH1A1GAA
SCHEMBL9011445 0.85 TSHR (0.70) PKMSMN1; SMN2TSHRALDH1A1GAA
SCHEMBL2824126 0.83 TSHR (0.61) PKMSMN1; SMN2TSHRCYP3A4NPSR1
SCHEMBL27787305 0.81 SMN1; SMN2 (0.55) PKMSMN1; SMN2TSHRCYP3A4CASP1
SCHEMBL11046227 0.81 PKM (0.55) PKMSMN1; SMN2TSHRCYP3A4NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4692381-A ELECTRIC WIRE AND CABLE INSULATION; PENNWALT CORPORATION (US) 1987-09-08 US claimed
US-4675345-A JACKETS AND COATINGS FOR CABLES AND TELEPHONE WIRES; DIELECTR ICS PENWALT CORPORATION (US) 1987-06-23 US claimed
US-4615850-A BLENDING WITH NUCLEATING AGENT, BLOWING AGENT; EXTRUSION PENNWALT CORPORATION (US) 1986-10-07 US claimed
EP-0169304-A1 Foamable polyvinylidene fluoride and a method for producing it PENNWALT CORPORATION (US) 1986-01-29 EP claimed
US-4692381-A ELECTRIC WIRE AND CABLE INSULATION; PENNWALT CORPORATION (US) 1987-09-08 US disclosed
US-4675345-A JACKETS AND COATINGS FOR CABLES AND TELEPHONE WIRES; DIELECTR ICS PENWALT CORPORATION (US) 1987-06-23 US disclosed
US-4615850-A BLENDING WITH NUCLEATING AGENT, BLOWING AGENT; EXTRUSION PENNWALT CORPORATION (US) 1986-10-07 US disclosed
EP-0169304-A1 Foamable polyvinylidene fluoride and a method for producing it PENNWALT CORPORATION (US) 1986-01-29 EP disclosed