Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15500025 | 0.94 | PIK3CD (0.33) | KMT2AASGR1PIK3CD | |
| SCHEMBL5319822 | 0.83 | LMNA (0.33) | KMT2ALMNASMN1; SMN2NPC1HPGD | |
| SCHEMBL6061650 | 0.83 | LMNA (0.33) | KMT2ALMNASMN1; SMN2NPC1HPGD | |
| SCHEMBL6293471 | 0.82 | LMNA (0.33) | KMT2ALMNASMN1; SMN2NPC1HPGD | |
| SCHEMBL15814830 | 0.77 | BCL2A1 (0.36) | LMNA | |
| SCHEMBL12711787 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL6046429 | 0.75 | — | — | |
| SCHEMBL14297424 | 0.73 | SMN1; SMN2 (0.33) | ASGR1PIK3CDSMN1; SMN2 | |
| SCHEMBL1962258 | 0.73 | NOS2 (0.36) | SMN1; SMN2 | |
| SCHEMBL8170965 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656263-A | 6-β-substituted penicillanic acid compound free of the 6-α-epimer | PFIZER INC. (US) | 1987-04-07 | — | — | US | disclosed |
| US-4518530-A | 6-β-Substituted penicillanic acids as β-lactamase inhibitors | PFIZER INC. (US) | 1985-05-21 | — | — | US | disclosed |
| US-4517126-A | Penicillanic acid derivative | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |