Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 3/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416746 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL141446 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL60410 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL6049861 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL28186389 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| Ammonia Solution, Strong SCHEMBL28791130 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL8800602 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| Ethane SCHEMBL9181718 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| Methane SCHEMBL4443817 | 0.72 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL10500101 | 0.72 | SOAT1 (0.42) | ALDH1A1HPGDHSD17B10LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4644008-A | Perhydroindole-2-carboxylic acids as antihypertensives | ADIR (FR) | 1987-02-17 | — | — | US | disclosed |
| US-4616031-A | Perhydroindole-2-carboxylic acids as antihypertensives | ADIR (FR) | 1986-10-07 | — | — | US | disclosed |
| US-4616030-A | Perhydroindole-2-carboxylic acids as antihypertensives | ADIR (FR) | 1986-10-07 | — | — | US | disclosed |
| US-4616029-A | Perhydromdole-2-carboxylic acids as antihypertensives | ADIR (FR) | 1986-10-07 | — | — | US | disclosed |
| US-4565819-A | ENZYME INHIBITORS, HYPOTENSIVE AGENTS | ADIR (FR) | 1986-01-21 | — | — | US | disclosed |
| US-4508729-A | Substituted iminodiacids, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1985-04-02 | — | — | US | disclosed |