Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 3/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749883 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HPGDLMNAHSD17B10ALOX15 | |
| SCHEMBL141446 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDLMNAHSD17B10ALOX15 | |
| Ammonia Solution, Strong SCHEMBL28791130 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10ALOX15 | |
| Ethane SCHEMBL9181718 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10ALOX15 | |
| SCHEMBL8800602 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10ALOX15 | |
| SCHEMBL28186389 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10ALOX15 | |
| SCHEMBL11228701 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL11068033 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1 | |
| SCHEMBL11063751 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5143571 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDLMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |