Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750748 | 1.00 | AHR (0.49) | AHRNR5A1TNNC1MAOAMAOB | |
| SCHEMBL13464287 | 0.91 | NR5A1 (0.54) | AHRNR5A1TNNC1MAOAMAOB | |
| SCHEMBL25779977 | 0.88 | AHR (0.49) | AHRNR5A1MAOAMAOBABCG2 | |
| SCHEMBL15661482 | 0.84 | RELA (0.54) | AHRTNNC1MAOBABCG2ESR1 | |
| SCHEMBL8619126 | 0.84 | AHR (0.48) | AHRNR5A1TNNC1MAOAMAOB | |
| SCHEMBL7239800 | 0.84 | TNNC1 (0.55) | AHRNR5A1TNNC1TP53TSHR | |
| SCHEMBL8619129 | 0.84 | AHR (0.48) | AHRNR5A1TNNC1MAOAMAOB | |
| SCHEMBL7239797 | 0.84 | TNNC1 (0.55) | AHRNR5A1TNNC1TP53TSHR | |
| SCHEMBL31618948 | 0.82 | AHR (0.51) | AHRNR5A1TNNC1ABCG2 | |
| SCHEMBL28710285 | 0.81 | TNNC1 (0.50) | AHRTNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195097-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | disclosed |
| US-4699995-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. (GB) | 1987-10-13 | — | — | US | disclosed |
| EP-0142145-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1987-03-04 | — | — | EP | disclosed |
| EP-0195097-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1986-09-24 | — | — | EP | disclosed |
| EP-0142145-A2 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1985-05-22 | — | — | EP | disclosed |