Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | PPOX | P50336 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | DTYMK | P23919 | 1/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889423 | 0.88 | MEN1 (0.55) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11282911 | 0.87 | MEN1 (0.54) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL6567226 | 0.85 | KDM4E (0.62) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL1028520 | 0.83 | TDP1 (0.46) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL6567283 | 0.82 | MEN1 (0.68) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10976077 | 0.81 | MEN1 (0.61) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL1028818 | 0.81 | KDM4E (0.54) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL27657761 | 0.80 | POLB (0.49) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11712839 | 0.80 | MAPT (0.52) | MEN1KMT2ATDP1TTRKDM4E | |
| SCHEMBL3890179 | 0.80 | TDP1 (0.56) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274280-A2 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | Biolipox AB (SE) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009127822-A2 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2009-10-22 | — | — | WO | disclosed |