Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368272 | 0.90 | TBXAS1 (0.73) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10749979 | 0.89 | TBXAS1 (0.71) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL6450638 | 0.84 | TBXAS1 (1.00) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10753330 | 0.83 | TBXAS1 (0.98) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL8580210 | 0.79 | TBXAS1 (0.79) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10751277 | 0.78 | TBXAS1 (0.77) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL10751611 | 0.77 | TBXAS1 (0.67) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL10761834 | 0.75 | TBXAS1 (0.61) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL10749747 | 0.75 | TBXAS1 (1.00) | TBXAS1ALDH1A1MAPK1LMNA | |
| SCHEMBL10751882 | 0.74 | TBXAS1 (1.00) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636500-A | N-(phenoxyalkyl)imidazoles as selective inhibitors of the thromboxane synthetase enzyme and pharmaceutical compositions thereof | PFIZER INC. (US) | 1987-01-13 | — | — | US | disclosed |
| US-4602016-A | N-(phenoxyalkyl)imidazoles as selective inhibitors of the thromboxane synthetase enzyme and pharmaceutical compositions thereof | PFIZER INC. (US) | 1986-07-22 | — | — | US | disclosed |