Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10751277 | 0.99 | TBXAS1 (0.77) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL10751882 | 0.84 | TBXAS1 (1.00) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL31634651 | 0.83 | ALDH1A1 (0.59) | TBXAS1ALDH1A1ALOX15LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL31634647 | 0.82 | ALDH1A1 (0.58) | TBXAS1ALDH1A1ALOX15LMNAMEN1 | |
| SCHEMBL6368272 | 0.82 | TBXAS1 (0.73) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10749979 | 0.81 | TBXAS1 (0.71) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL10751609 | 0.79 | TBXAS1 (0.73) | TBXAS1ALDH1A1ALOX15MAPK1HSD17B10 | |
| Fumaric Acid SCHEMBL31634648 | 0.78 | ALDH1A1 (0.57) | TBXAS1ALDH1A1ALOX15LMNAMEN1 | |
| SCHEMBL10370478 | 0.76 | TBXAS1 (1.00) | TBXAS1ALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL10651065 | 0.76 | CYP19A1 (0.57) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925869-A | REACTIVATING ENZYME ACETYLCHOLINESTERASE INHIBITED BY LETHAL DOSE OF SOMAN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | claimed |
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | disclosed |