Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757179 | 0.86 | SMN1; SMN2 (0.49) | KDM4EMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10751359 | 0.85 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALDH1A1GAAPDE4B | |
| SCHEMBL11159813 | 0.84 | MAPT (0.40) | KDM4EMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11599823 | 0.84 | ALDH1A1 (0.45) | MAPTSMN1; SMN2ALDH1A1GAAPDE4B | |
| SCHEMBL17542331 | 0.84 | KDM4E (0.37) | KDM4EMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27588870 | 0.83 | KDM4E (0.46) | KDM4EMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10754583 | 0.81 | ALDH1A1 (0.46) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10755815 | 0.79 | HTT (0.52) | KDM4EMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10751425 | 0.79 | SRD5A2 (0.45) | KDM4EMAPTSMN1; SMN2GAALMNA | |
| SCHEMBL10755186 | 0.79 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687858-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1987-08-18 | — | — | US | disclosed |
| US-4508910-A | Herbicidal 4-benzoyl-5-hydroxy-pyrazales | SANKYO COMPANY LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| US-4414392-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY, LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4301293-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LTD. (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4261729-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4146726-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4063925-A | Herbicidal compositions | SANKYO COMPANY LIMITED (JA) | 1977-12-20 | — | — | US | disclosed |