Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751359 | 0.99 | ALDH1A1 (0.46) | ALDH1A1GAALMNAPOLBCES2 | |
| SCHEMBL11635778 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAALMNAPOLBCES2 | |
| SCHEMBL10752053 | 0.84 | KDM4E (0.40) | ALDH1A1GAALMNANR3C1KMT2A | |
| SCHEMBL10750845 | 0.84 | ENPP3 (0.44) | ALDH1A1POLBKMT2AMAPTSPR | |
| SCHEMBL10752306 | 0.83 | KMT2A (0.51) | LMNAPOLBKMT2AMAPTNPC1 | |
| SCHEMBL10755502 | 0.82 | POLB (0.40) | ALDH1A1LMNAPOLBKMT2AMAPT | |
| SCHEMBL10751550 | 0.82 | MAPT (0.43) | ALDH1A1LMNAKMT2AMAPTSPR | |
| SCHEMBL1324474 | 0.82 | KMT2A (0.52) | LMNAPOLBKMT2AMAPTNPC1 | |
| SCHEMBL10990668 | 0.82 | ALDH1A1 (0.44) | ALDH1A1GAALMNAPOLBCES2 | |
| SCHEMBL10750310 | 0.81 | POLB (0.40) | ALDH1A1LMNAPOLBNR3C1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070536-A | Process for the preparation of 4-benzoylpyrazole derivatives | SANKYO COMPANY LIMITED (JA) | 1978-01-24 | — | — | US | disclosed |