Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796653 | 0.85 | FFAR1 (0.48) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL10796659 | 0.82 | FFAR1 (0.46) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL8846233 | 0.81 | GGPS1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL8846716 | 0.81 | GGPS1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1852576 | 0.81 | KCNH2 (0.48) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL10795164 | 0.81 | KCNH2 (0.48) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL7680519 | 0.81 | KCNH2 (0.48) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL8846088 | 0.81 | KCNH2 (0.48) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL9700186 | 0.80 | KCNH2 (0.45) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL9150614 | 0.78 | NR1I2 (0.52) | FFAR1FFAR4MMP2MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195097-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | claimed |
| US-4699995-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. (GB) | 1987-10-13 | — | — | US | claimed |
| EP-0142145-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1987-03-04 | — | — | EP | claimed |
| EP-0195097-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1986-09-24 | — | — | EP | claimed |
| EP-0142145-A2 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1985-05-22 | — | — | EP | claimed |