Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846716 | 1.00 | GGPS1 (0.44) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL9145650 | 0.93 | GGPS1 (0.45) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL9150614 | 0.86 | NR1I2 (0.52) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL10752111 | 0.81 | FFAR1 (0.47) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL8846088 | 0.80 | KCNH2 (0.48) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL1852576 | 0.80 | KCNH2 (0.48) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL7680519 | 0.80 | KCNH2 (0.48) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL10795164 | 0.80 | KCNH2 (0.48) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL10796653 | 0.80 | FFAR1 (0.48) | GGPS1KCNH2FFAR1FFAR4MMP2 | |
| SCHEMBL9700186 | 0.79 | KCNH2 (0.45) | GGPS1KCNH2FFAR1FFAR4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504237-A | PLA2 inhibitors | MONSANTO COMPANY (US) | 1996-04-02 | — | — | US | claimed |
| US-5648349-A | PHOSPHOLIPASE INHIBITORS | MONSANTO COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5504237-A | PLA2 inhibitors | MONSANTO COMPANY (US) | 1996-04-02 | — | — | US | disclosed |