Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | BLM | P54132 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754151 | 0.94 | CYP19A1 (0.41) | CYP19A1KMT2AMEN1BLMALDH1A1 | |
| SCHEMBL10883313 | 0.91 | KMT2A (0.49) | CYP19A1KMT2AMEN1BLMALDH1A1 | |
| SCHEMBL1478995 | 0.84 | CYP19A1 (0.57) | CYP19A1KMT2AMEN1BLMALDH1A1 | |
| SCHEMBL11046399 | 0.84 | CYP19A1 (0.57) | CYP19A1KMT2AMEN1BLMALDH1A1 | |
| SCHEMBL1906406 | 0.77 | KMT2A (0.56) | CYP19A1KMT2AMEN1BLMALDH1A1 | |
| SCHEMBL10895797 | 0.70 | BLM (0.50) | CYP19A1KMT2AMEN1BLMALDH1A1 | |
| SCHEMBL5420918 | 0.69 | KMT2A (0.57) | KMT2AMEN1BLMALDH1A1MAPK1 | |
| SCHEMBL10894911 | 0.69 | BLM (0.50) | CYP19A1KMT2AMEN1BLMALDH1A1 | |
| SCHEMBL2531942 | 0.67 | MAOA (0.58) | KMT2AMEN1BLMALDH1A1MAPK1 | |
| SCHEMBL30587670 | 0.67 | MAOA (0.58) | KMT2AMEN1BLMALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62059668-A | — | — | None | — | — | JP | disclosed |
| JP-S6259668-A | NAPHTHALENE DERIVATIVE | SHISEIDO CO LTD | 1987-03-16 | — | — | JP | disclosed |