Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866859 | 0.86 | KCNH2 (0.41) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10751705 | 0.84 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10751178 | 0.79 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Hydrochloric Acid SCHEMBL10914785 | 0.79 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9540550 | 0.78 | KCNH2 (0.50) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Hydrochloric Acid SCHEMBL10862782 | 0.78 | KCNH2 (0.41) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8336517 | 0.77 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9539400 | 0.76 | KCNH2 (0.47) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9537686 | 0.76 | KCNH2 (0.58) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8559728 | 0.76 | ALDH1A1 (0.52) | ALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208210-A1 | Pyridonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |