Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543158 | 0.88 | POLB (0.40) | BRD4POLBKMT2AALDH1A1 | |
| SCHEMBL8600205 | 0.88 | POLB (0.40) | BRD4POLBKMT2AALDH1A1 | |
| SCHEMBL10755843 | 0.81 | KMT2A (0.40) | KMT2AATMALDH1A1 | |
| SCHEMBL21955913 | 0.79 | KMT2A (0.54) | BRD4POLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7828421 | 0.78 | ATM (0.42) | POLBKMT2AATM | |
| SCHEMBL8597022 | 0.78 | ATM (0.42) | POLBKMT2AATM | |
| SCHEMBL10699678 | 0.77 | ERCC1 (0.41) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10700782 | 0.77 | MEN1 (0.43) | KMT2AKDM4EATMALDH1A1SMN1; SMN2 | |
| SCHEMBL10493322 | 0.77 | CTSL (0.40) | CYP2D6CYP2C9CYP2C19KMT2AATM | |
| SCHEMBL10751872 | 0.77 | MEN1 (0.52) | POLBKMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684641-A | BACTERICIDES | PFIZER INC. (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0168177-A2 | Cephalosporin antibiotics | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | disclosed |