Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543158 | 1.00 | POLB (0.40) | POLBMEN1KMT2ACCKBRMAPT | |
| SCHEMBL7828421 | 0.90 | ATM (0.42) | POLBMEN1KMT2ACCKBRMAPT | |
| SCHEMBL8597022 | 0.90 | ATM (0.42) | POLBMEN1KMT2ACCKBRMAPT | |
| SCHEMBL28435235 | 0.89 | MAPT (0.43) | POLBMEN1KMT2AMAPTPDE3A | |
| SCHEMBL28473803 | 0.89 | MAPT (0.43) | POLBMEN1KMT2AMAPTPDE3A | |
| Water SCHEMBL8600954 | 0.89 | ATM (0.42) | POLBMEN1KMT2ACCKBRMAPT | |
| SCHEMBL9814590 | 0.88 | MEN1 (0.38) | POLBMEN1KMT2ACCKBRMAPT | |
| SCHEMBL10372875 | 0.88 | GPR88 (0.39) | POLBMEN1KMT2ACCKBRMAPT | |
| SCHEMBL10754281 | 0.88 | BRD4 (0.43) | POLBKMT2AALDH1A1BRD4 | |
| SCHEMBL11093687 | 0.85 | MC4R (0.37) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820999-A1 | A process for the preparation of penicillins | Ribbon S.r.L. (IT) | 1998-01-28 | — | — | EP | disclosed |
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |
| EP-0754184-A1 | CEPHALOSPORIN ANTIBIOTICS | Microcide Pharmaceuticals, Inc. (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5593986-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1995026966-A1 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-4971963-A | BACTERICIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4940702-A | Cephem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-10 | — | — | US | disclosed |
| US-4647558-A | MONOCYCLIC B-LACTAM ANTIBIOTIC | BEECHAM GROUP P.L.C. (GB) | 1987-03-03 | — | — | US | disclosed |
| EP-0211656-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-02-25 | — | — | EP | disclosed |
| EP-0088488-B1 | ANTIBACTERIAL AGENTS, THEIR PREPARATION AND USE | BEECHAM GROUP PLC (GB) | 1986-10-01 | — | — | EP | disclosed |
| EP-0168177-A2 | Cephalosporin antibiotics | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | disclosed |
| EP-0114752-A2 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1984-08-01 | — | — | EP | disclosed |
| EP-0114750-A2 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1984-08-01 | — | — | EP | disclosed |
| EP-0086563-A1 | Antibacterial agents, their preparation and use | BEECHAM GROUP PLC (GB) | 1983-08-24 | — | — | EP | disclosed |
| US-4226864-A | BACTERICIDES, ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1980-10-07 | — | — | US | disclosed |
| US-4200744-A | Substituted 7α-methoxy-7β[(2,3-dioxo-1-piperazinyl)carbonylaminophenylacetamido]cephalosporins | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1980-04-29 | — | — | US | disclosed |
| US-4129730-A | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 1978-12-12 | — | — | US | disclosed |