Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602068 | 0.79 | HRH3 (0.57) | HRH3KCNH2PDE3APDE3BCYP26A1 | |
| Hydrochloric Acid SCHEMBL7314082 | 0.78 | HRH3 (0.56) | HRH3KCNH2PDE3APDE3BPDE4B | |
| SCHEMBL10751517 | 0.78 | HRH3 (0.49) | HRH3KCNH2PDE3APDE3BPDE4B | |
| SCHEMBL10753296 | 0.77 | HRH3 (0.54) | HRH3KCNH2PDE3APDE3BPDE4B | |
| SCHEMBL8305150 | 0.77 | HRH3 (0.54) | HRH3KCNH2PDE3APDE3B | |
| SCHEMBL10341508 | 0.75 | PDE3B (0.53) | HRH3KCNH2PDE3APDE3B | |
| SCHEMBL10341530 | 0.75 | HRH3 (0.53) | HRH3KCNH2PDE3APDE3B | |
| SCHEMBL10753732 | 0.75 | HRH3 (0.46) | HRH3KCNH2PDE3APDE3B | |
| SCHEMBL21970124 | 0.74 | HRH3 (0.48) | HRH3KCNH2PDE3APDE3B | |
| SCHEMBL10341521 | 0.74 | HRH3 (0.62) | HRH3KCNH2PDE3APDE3BPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692447-A | HYPOTENSIVE, VASODILATOR, ANTITHROMBOTIC, ANTIAGGREGANT, CYTOPROTECTIVE | BOEHRINGER BIOCHEMIA ROBIN, S.P.A. (IT) | 1987-09-08 | — | — | US | disclosed |