SCHEMBL1075474

SCHEMBL1075474

O=C(Cl)c1cc(I)c(I)c(C(=O)Cl)c1I

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.37
ALDH1A1 P00352 2/20 0.32
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31166668 1.00 TPMT (0.37) TPMTALDH1A1ALOX15
SCHEMBL28612017 0.82 TPMT (0.39) TPMTALDH1A1ALOX15
SCHEMBL13287027 0.76 ALDH1A1 (0.37) TPMTALDH1A1ALOX15
SCHEMBL879357 0.76 TTR (0.39) TPMTALDH1A1ALOX15
SCHEMBL29367522 0.76 TTR (0.39) TPMTALDH1A1ALOX15
Hydrochloric Acid SCHEMBL23524594 0.74 TTR (0.37) TPMTALDH1A1ALOX15
SCHEMBL28283179 0.74 TPMT (0.37) TPMTALDH1A1
SCHEMBL28669965 0.74 ALDH1A1 (0.37) ALDH1A1ALOX15
SCHEMBL28278150 0.74 TPMT (0.32) TPMTALDH1A1ALOX15
SCHEMBL31232360 0.73 TPMT (0.39) TPMTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116421744-A Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2023-07-14 CN claimed
CN-108821990-A A kind of preparation method of 5- amino -2,4,6- triiodo isophthaloyl chlorine 浙江海洲制药有限公司 2018-11-16 CN claimed
CN-103965074-B A kind of new method synthesizing Iopromide 淮海工学院 2016-10-05 CN claimed
CN-103965074-A Novel synthesis method for iopromide HUAIHAI INST TECHNOLOGY 2014-08-06 CN claimed
CN-116421744-B Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2024-02-09 CN disclosed
CN-116421744-A Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2023-07-14 CN disclosed
CN-107237133-B A kind of preparation method of the anti-radiation fiber of tree cotton 广西玉林魔树树棉科技有限公司 2019-08-13 CN disclosed
CN-107237133-B A kind of preparation method of the anti-radiation fiber of tree cotton 广西玉林魔树树棉科技有限公司 2019-08-13 CN disclosed
CN-108947959-A A kind of preparation method of non-ionic diodone intermediate 正大天晴药业集团股份有限公司 2018-12-07 CN disclosed
CN-108821990-A A kind of preparation method of 5- amino -2,4,6- triiodo isophthaloyl chlorine 浙江海洲制药有限公司 2018-11-16 CN disclosed
CN-108821990-A A kind of preparation method of 5- amino -2,4,6- triiodo isophthaloyl chlorine 浙江海洲制药有限公司 2018-11-16 CN disclosed
CN-105636933-B The method for preparing the intermediate of Iopromide 大熊制药株式会社 2017-12-15 CN disclosed
CN-103570580-A Preparation method of high-purity iopromide BEIJING JINGWEI XINKANG MEDICAL TECHNOLOGY DEV CO LTD 2014-02-12 CN disclosed
CN-102351735-B Preparation method of Iopromide ZHEJIANG STARRY PHARMACEUTICAL CO LTD 2012-10-10 CN disclosed
CN-102351735-A Preparation method of Iopromide ZHEJIANG STARRY PHARMACEUTICAL CO LTD 2012-02-15 CN disclosed
EP-1989179-B1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2011-01-26 EP disclosed
EP-1989179-A1 CONTRAST AGENTS GE Healthcare AS (NO) 2008-11-12 EP disclosed
WO-2007094683-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2007-08-23 WO disclosed
WO-1999056787-A1 SELECTION OF CONTRAST AGENT FROM A COMBINATORIAL LIBRARY NYCOMED IMAGING AS (NO) 1999-11-11 WO disclosed
WO-1999056788-A1 SELECTION OF TARGETED CONTRAST AGENTS FROM A COMBINATORIAL LIBRARY NYCOMED IMAGING AS (NO) 1999-11-11 WO disclosed