SCHEMBL28612017

SCHEMBL28612017

O=C(Cl)c1cc(I)c(I)c(I)c1I

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.39
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1075474 0.82 TPMT (0.37) TPMTALDH1A1ALOX15
SCHEMBL28278150 0.82 TPMT (0.32) TPMTALDH1A1ALOX15
SCHEMBL31166668 0.82 TPMT (0.37) TPMTALDH1A1ALOX15
SCHEMBL13287027 0.79 ALDH1A1 (0.37) TPMTALDH1A1ALOX15TP53
SCHEMBL29367522 0.79 TTR (0.39) TPMTALDH1A1ALOX15
SCHEMBL879357 0.79 TTR (0.39) TPMTALDH1A1ALOX15
SCHEMBL3371190 0.78 TPMT (0.52) TPMTALDH1A1ALOX15TP53
Hydrochloric Acid SCHEMBL23524594 0.77 TTR (0.37) TPMTALDH1A1ALOX15
SCHEMBL28283179 0.77 TPMT (0.37) TPMTALDH1A1TP53
SCHEMBL617323 0.76 ALDH1A1 (0.37) TPMTALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111184877-B Nano contrast medium for electronic computer tomography imaging and preparation method thereof 同济大学 2021-08-06 CN disclosed
CN-111184877-A Nano contrast medium for electronic computer tomography imaging and preparation method thereof 同济大学 2020-05-22 CN disclosed