Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757683 | 0.86 | OPRM1 (0.39) | BRD4OPRM1KDM4EMEN1MAPT | |
| SCHEMBL7301462 | 0.85 | BRD4 (0.54) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL10427679 | 0.85 | BRD4 (0.43) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL10615273 | 0.85 | MTNR1B (0.41) | — | |
| SCHEMBL10617763 | 0.81 | BRD4 (0.40) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL10763102 | 0.79 | KMT2A (0.45) | BRD4CYP1A2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23856939 | 0.79 | BRD4 (0.43) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL30253303 | 0.79 | BRD4 (0.43) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL3309675 | 0.78 | BRD4 (0.50) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL9770095 | 0.78 | BRD4 (0.50) | BRD4OPRM1OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234113-A1 | 2,3-Dihydro-1H-phenalene-2-amino compounds as anti-psychotic drugs | THE UPJOHN COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |