Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190037 | 0.88 | OPRD1 (0.47) | TSHRCTSSCTSKCTSLMME | |
| SCHEMBL10756817 | 0.84 | OPRD1 (0.56) | MMEOPRK1ACECPA1ACE2 | |
| SCHEMBL10758438 | 0.84 | OPRD1 (0.56) | MMEOPRK1ACECPA1ACE2 | |
| SCHEMBL22461945 | 0.80 | CHRND (0.47) | CTSSCTSKCTSL | |
| SCHEMBL10760221 | 0.79 | OPRD1 (0.44) | TSHRCA12CA1CA2CA3 | |
| SCHEMBL9724062 | 0.78 | GRIA1 (0.59) | CTSSCTSKCTSLOPRK1ACE | |
| SCHEMBL16656679 | 0.78 | GRIA1 (0.46) | CTSSCTSKCTSLOPRK1OPRD1 | |
| SCHEMBL21415384 | 0.78 | GRIA1 (0.46) | CTSSCTSKCTSLOPRK1OPRD1 | |
| SCHEMBL16217709 | 0.78 | GRIA1 (0.46) | CTSSCTSKCTSLOPRK1OPRD1 | |
| SCHEMBL12126314 | 0.78 | ACE (0.60) | CTSSCTSKCTSLMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122018-B1 | IMPROVEMENTS IN AND RELATING TO PHARMACOLOGICALLY ACTIVE TRIPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-09-02 | — | — | EP | claimed |
| US-4510082-A | NONHABIT-FORMING ANALGESICS | ELI LILLY AND COMPANY (US) | 1985-04-09 | — | — | US | claimed |
| EP-0122018-A2 | Improvements in and relating to pharmacologically active tripeptide derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | claimed |
| EP-0122018-B1 | IMPROVEMENTS IN AND RELATING TO PHARMACOLOGICALLY ACTIVE TRIPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| US-4510082-A | NONHABIT-FORMING ANALGESICS | ELI LILLY AND COMPANY (US) | 1985-04-09 | — | — | US | disclosed |
| EP-0122018-A2 | Improvements in and relating to pharmacologically active tripeptide derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |