Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.47 |
| ▸ | CHRNG | P07510 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254362 | 0.87 | L3MBTL1 (0.51) | CTSLCTSSCTSK | |
| SCHEMBL23177850 | 0.87 | L3MBTL1 (0.51) | CTSLCTSSCTSK | |
| SCHEMBL19477907 | 0.84 | CHRND (0.54) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL19477879 | 0.84 | CYP3A4 (0.50) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL19477908 | 0.82 | CHRND (0.61) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL15359366 | 0.81 | GRIA1 (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL10756316 | 0.80 | TSHR (0.46) | CTSLCTSSCTSK | |
| SCHEMBL8022821 | 0.79 | MMP1 (0.51) | CTSLESR1ESR2 | |
| SCHEMBL7029376 | 0.79 | MMP1 (0.51) | CTSLESR1ESR2 | |
| SCHEMBL21415384 | 0.78 | GRIA1 (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113820-A1 | CONJUGATES AND METHODS FOR TREATING LIVER FIBROSIS | GENEVANT SCIENCES GMBH (CH) | 2021-06-10 | — | — | WO | disclosed |
| WO-2020191207-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-09-24 | — | — | WO | disclosed |