SCHEMBL107565

SCHEMBL107565

FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.52
CES2 O00748 1/20 0.41
DAO P14920 2/20 0.40
TAAR1 Q96RJ0 1/20 0.38
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
TACR1 P25103 4/20 0.37
MTOR P42345 1/20 0.37
CACNA1F O60840 1/20 0.37
CACNA1D Q01668 1/20 0.37
CACNA1S Q13698 1/20 0.37
CACNA1C Q13936 1/20 0.37
TSHR P16473 1/20 0.37
MLYCD O95822 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27149375 0.97 IDO1 (0.50) IDO1CES2DAOTAAR1RXRA
Hydroquinone SCHEMBL28540141 0.87 IDO1 (0.47) IDO1RXRARXRBRXRGTACR1
SCHEMBL29738521 0.86 IDO1 (0.41) IDO1CES2DAOTAAR1MTOR
SCHEMBL3591051 0.86 IDO1 (0.41) IDO1CES2DAOTAAR1MTOR
SCHEMBL56666 0.86 IDO1 (0.41) IDO1DAOTAAR1RXRARXRB
SCHEMBL29738541 0.86 IDO1 (0.41) IDO1DAOTAAR1RXRARXRB
SCHEMBL18740304 0.84 IDO1 (0.39) IDO1CES2DAOTAAR1TSHR
SCHEMBL1229494 0.84 IDO1 (0.39) IDO1TACR1TSHRCYP3A4CYP2D6
SCHEMBL799078 0.84 IDO1 (0.39) IDO1DAOTACR1
SCHEMBL6602321 0.81 IDO1 (0.37) IDO1CES2TAAR1TACR1CACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282729-A1 CHEMICAL COMPOUND MANUFACTURE, NEW SALT FORM, AND THERAPEUTIC USES THEREOF EUSTRALIS PHARMACEUTICALS LIMITED (TRADING AS PRESSURA NEURO) (AU) 2025-09-11 US claimed
US-12351557-B2 Chemical compound manufacture, new salt form, and therapeutic uses thereof EUSTRALIS PHARMACEUTICALS LIMITED (AU) 2025-07-08 US claimed
CN-119751477-A Lipid drop and hypochlorous acid sequence response type fluorescent probe and synthetic method and application thereof 南宁师范大学 2025-04-04 CN claimed
CN-119431278-A Aromatic oxetanes and their use in encapsulation compositions 华为技术有限公司 2025-02-14 CN claimed
CN-117700368-A Synthesis method of pentanitrogen guanidine salt chiral phase transfer catalyst 四川大学 2024-03-15 CN claimed
CN-117486852-A Fluorine-containing rotaxane molecule and preparation method and application thereof 中国科学院精密测量科学与技术创新研究院 2024-02-02 CN claimed
CN-113549062-B Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof 南京工业大学 2022-08-09 CN claimed
US-20220073467-A1 Chemical Compound Manufacture, New Salt Form, And Therapeutic Uses Thereof EUSTRALIS PHARMACEUTICALS LIMITED (TRADING AS PRESSURA NEURO) (AU) 2022-03-10 US claimed
EP-3902793-A1 CHEMICAL COMPOUND MANUFACTURE, NEW SALT FORM, AND THERAPEUTIC USES THEREOF Eustralis Pharmaceuticals Limited (Trading as Pressura Neuro) (AU) 2021-11-03 EP claimed
WO-2020132716-A1 CHEMICAL COMPOUND MANUFACTURE, NEW SALT FORM, AND THERAPEUTIC USES THEREOF EUSTRALIS PHARMACEUTICALS LIMITED (TRADING AS PRESSURA NEURO) (AU) 2020-07-02 WO claimed
CN-104181772-B Two-photon activity photo-acid agent of the one kind using biphenyl as conjugated structure, preparation method and applications 同济大学 2018-07-03 CN claimed
CN-104181772-A Two-photon active photoacid generators taking biphenyl as conjugated structure and preparation method and application of two-photon active photoacid generators UNIV TONGJI 2014-12-03 CN claimed
US-7776952-B2 Polymeric dispersant having an affinity with a supercritical fluid SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-08-17 US claimed
EP-1344772-B1 ARYLBIS (PERFLUOROALKYLSULFONYL) METHANE, METAL SALT OF THE SAME, AND PROCESSES FOR PRODUCING THESE JAPAN SCIENCE & TECH AGENCY (JP) 2009-07-22 EP claimed
US-7339082-B2 Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-03-04 US claimed
US-20080039404-A1 BIFUNCTIONAL ANALGESIC COMPOUNDS FOR OPIOID RECEPTOR AGONISTS AND NEUROKININ-1 RECEPTOR ANTAGONISTS UNIVERSITY OF ARIZONA (US) 2008-02-14 US claimed
US-20060160946-A1 Polymeric dispersant having an affinity with a supercritical fluid SAMSUNG ELECTRONICS CO., LTD. 2006-07-20 US claimed
US-20050070741-A1 Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same ISHIHARA KAZUAKI (JP) 2005-03-31 US claimed
US-20040030192-A1 Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof and methods for producing the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2004-02-12 US claimed
EP-1344772-A1 ARYLBIS (PERFLUOROALKYLSULFONYL) METHANE, METAL SALT OF THE SAME, AND PROCESSES FOR PRODUCING THESE Japan Science and Technology Corporation (JP) 2003-09-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050070741-A1 Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same TTI1, TTI2, TST IDO1 3337/4885CES2 2419/4885DAO 1268/4885
US-20250282729-A1 CHEMICAL COMPOUND MANUFACTURE, NEW SALT FORM, AND THERAPEUTIC USES THEREOF SCN5A, MGMT, NISCH IDO1 2316/4885CES2 1699/4885DAO 2189/4885
US-20040030192-A1 Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof and methods for producing the same TTI1, TTI2, FLI1 IDO1 3456/4885CES2 2321/4885DAO 1467/4885
US-12351557-B2 Chemical compound manufacture, new salt form, and therapeutic uses thereof SCN5A, MGMT, NISCH IDO1 2316/4885CES2 1699/4885DAO 2189/4885
US-20220073467-A1 Chemical Compound Manufacture, New Salt Form, And Therapeutic Uses Thereof SCN5A, MGMT, NISCH IDO1 2316/4885CES2 1699/4885DAO 2189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.