SCHEMBL10756643

SCHEMBL10756643

OCCc1ccc(Br)c(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
ALOX5 P09917 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
BACE1 P56817 1/20 0.52
CA2 P00918 2/20 0.46
TDP1 Q9NUW8 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4977889 0.82 KDM4E (0.65) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL15921609 0.80 KDM4E (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL3085307 0.80 KDM4E (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL31753689 0.80 ALDH1A1 (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL1099654 0.80 ALDH1A1 (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL11279849 0.80 ALDH1A1 (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL4599785 0.80 CYP1A2 (0.53) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL2299809 0.80 ALDH1A1 (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL2302020 0.80 KDM4E (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL29434697 0.80 ALDH1A1 (0.47) KDM4EALDH1A1ALOX5GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020155595-A1 AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR 清华大学 2020-08-06 WO disclosed
US-4683234-A HYPOTENSIVE AGENTS, ANTI-ANGINA SUNTORY LIMITED (JP) 1987-07-28 US disclosed
EP-0162208-A2 Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1985-11-27 EP disclosed