Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528973 | 0.89 | ALOX15 (0.54) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL3190378 | 0.84 | ALOX15 (0.58) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL1390986 | 0.82 | ALOX15 (0.52) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL29987473 | 0.82 | ALOX15 (0.52) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL10756643 | 0.82 | KDM4E (0.52) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL3699399 | 0.81 | CNR1 (0.64) | KDM4EALOX5BACE1ALOX15CA2 | |
| SCHEMBL4617657 | 0.81 | ALOX15 (0.46) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL517444 | 0.81 | TAAR1 (0.67) | KDM4EMAPTALDH1A1GAABACE1 | |
| Hydroxytyrosol SCHEMBL44363 | 0.79 | MAPT (1.00) | KDM4EMAPTALDH1A1GAAALOX5 | |
| Hydroxytyrosol SCHEMBL29414541 | 0.79 | MAPT (1.00) | KDM4EMAPTALDH1A1GAAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457171-B | Synthetic method of hydroxytyrosol | 深圳市迪克曼科技开发有限公司 | 2021-05-14 | — | — | CN | claimed |
| CN-112457171-A | Synthetic method of hydroxytyrosol | 深圳市迪克曼科技开发有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-117326917-B | Hydroxytyrosol and high-purity large-scale synthesis method thereof | 锦州奥鸿药业有限责任公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-116888125-B | TYK2 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117326917-A | Hydroxytyrosol and high-purity large-scale synthesis method thereof | 锦州奥鸿药业有限责任公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-116888125-A | TYK2 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2022213980-A1 | TYK2 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2022-10-13 | — | — | WO | disclosed |
| CN-114931519-A | Synthesis method of hydroxytyrosol and derivatives thereof and application of hydroxytyrosol and derivatives thereof in cosmetics | 上海贤鼎生物科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-112457171-B | Synthetic method of hydroxytyrosol | 深圳市迪克曼科技开发有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-112457171-B | Synthetic method of hydroxytyrosol | 深圳市迪克曼科技开发有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-112457171-A | Synthetic method of hydroxytyrosol | 深圳市迪克曼科技开发有限公司 | 2021-03-09 | — | — | CN | disclosed |
| US-20040142930-A1 | Cyclic compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-20040058930-A1 | Thiophene-based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY | 2004-03-25 | — | — | US | disclosed |
| US-20030229089-A1 | Cyclic compounds | TANABE SEIYAKU CO., LTD. (JP) | 2003-12-11 | — | — | US | disclosed |
| WO-2003084959-A1 | THIOPENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-10-16 | — | — | WO | disclosed |
| CN-1440393-A | cyclic compound | TANABE SEIYAKU CO (JP) | 2003-09-03 | — | — | CN | disclosed |
| EP-1277741-A1 | CYCLIC COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2003-01-22 | — | — | EP | disclosed |
| EP-1179025-A1 | SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME | Cryovac, Inc. (US) | 2002-02-13 | — | — | EP | disclosed |
| US-6197715-B1 | USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS | CRYOVAC, INC. | 2001-03-06 | — | — | US | disclosed |
| WO-2000056787-A1 | SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME | CRYOVAC, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058930-A1 | Thiophene-based tricyclic compounds and pharmaceutical compositions comprising same | ABCG2, PFAS, CYP2F1 | KDM4E 3793/4885MAPT 2887/4885ALDH1A1 1156/4885 |
| US-20030229089-A1 | Cyclic compounds | PDE3B, PDE5A, PDE9A | KDM4E 999/4885MAPT 4760/4885ALDH1A1 1341/4885 |
| US-20040142930-A1 | Cyclic compounds | PDE3B, PDE4A, PDE5A | KDM4E 732/4885MAPT 4747/4885ALDH1A1 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.