Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921197 | 0.76 | HRH3 (0.50) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL10509547 | 0.73 | NPC1 (0.49) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL5158090 | 0.73 | NPC1 (0.49) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL5256809 | 0.73 | PLD1 (0.46) | ALDH1A1KDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL31192169 | 0.72 | PDE10A (0.48) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL3559837 | 0.72 | PDE10A (0.48) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL30376172 | 0.71 | HTR2A (0.54) | ALDH1A1KDM4ELMNAKMT2AGMNN | |
| SCHEMBL28477055 | 0.71 | HTR2A (0.54) | ALDH1A1KDM4ELMNAKMT2AGMNN | |
| SCHEMBL8588025 | 0.70 | HTR3E (0.59) | ALDH1A1KDM4ECYP3A4HTTPMP22 | |
| SCHEMBL10507905 | 0.70 | GAA (0.54) | PDE10ANPC1RAB9AMTORHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230239-A2 | Naphthyridine derivatives, process for their preparation and their use as agents with a herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | disclosed |
| EP-0230239-A2 | Naphthyridine derivatives, process for their preparation and their use as agents with a herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | disclosed |