SCHEMBL5256809

SCHEMBL5256809

C1=NCCN1c1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLD1 Q13393 1/20 0.46
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 7/20 0.40
HPGD P15428 4/20 0.40
HSD17B10 Q99714 4/20 0.40
CRBN Q96SW2 1/20 0.40
ALOX5 P09917 1/20 0.40
CYP1A2 P05177 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
USP2 O75604 2/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28735051 0.90 PLD1 (0.39) PLD1KDM4EALDH1A1HPGDHSD17B10
Thiourea SCHEMBL28833597 0.90 KDM4E (0.41) PLD1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9375555 0.75 KDM4E (0.38) KDM4EALDH1A1SMN1; SMN2USP2TSHR
SCHEMBL29118397 0.73 MAOB (0.37) KDM4EALDH1A1
SCHEMBL3078996 0.73 GRIN2B (0.46) PLD1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL10757283 0.73 ALDH1A1 (0.39) KDM4EALDH1A1SMN1; SMN2TSHRMEN1
SCHEMBL8887155 0.72 COMT (0.43) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL6272216 0.71 SIGMAR1 (0.41) KDM4EHPGDHSD17B10SMN1; SMN2MEN1
SCHEMBL105023 0.71 SIGMAR1 (0.41) KDM4EHPGDHSD17B10SMN1; SMN2MEN1
SCHEMBL1140766 0.71 PLD1 (0.47) PLD1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 EP claimed
EP-4069709-A1 METAL COMPLEXES Merck Patent GmbH (DE) 2022-10-12 EP claimed
CN-111170918-B Method for synthesizing gamma-lactam and delta-lactam through C-H amine 山东大学 2021-09-21 CN claimed
WO-2021110720-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2021-06-10 WO claimed
CN-111170918-A Method for synthesizing gamma-lactam and delta-lactam through C-H amine 山东大学 2020-05-19 CN claimed
EP-2872590-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-11-14 EP claimed
EP-2906575-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-01-17 EP claimed
CN-106810533-A A kind of chiral compound and preparation method and metal complex containing '-imine pyridinyl imidazoline 浙江大学 2017-06-09 CN claimed
EP-2872590-A1 METAL COMPLEXES Merck Patent GmbH (DE) 2015-05-20 EP claimed
WO-2014008982-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2014-01-16 WO claimed
EP-1751152-A2 AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE Bayer CropScience Aktiengesellschaft (DE) 2007-02-14 EP claimed
WO-2005113553-A2 AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE BAYER CROPSCIENCE AG (DE) 2005-12-01 WO claimed
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 EP disclosed
CN-116283921-B Corrosion inhibitor for carbon dioxide huff and puff well and preparation method thereof 天津中油科远石油工程有限责任公司 2024-09-17 CN disclosed
CN-116283921-B Corrosion inhibitor for carbon dioxide huff and puff well and preparation method thereof 天津中油科远石油工程有限责任公司 2024-09-17 CN disclosed
CN-116283921-A Corrosion inhibitor for carbon dioxide huff and puff well and preparation method thereof 天津中油科远石油工程有限责任公司 2023-06-23 CN disclosed
US-4404012-A APPLYING A 2-(2-IMIDAZOLIN-2-YL) PYRIDINE COMPOUND AMERICAN CYANAMID COMPANY (US) 1983-09-13 US disclosed
EP-0041623-A2 Substituted imidazolinyl nicotine acids, esters and salts and use thereof as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1981-12-16 EP disclosed
EP-0041624-A2 Method to beneficially influence & alter the development & life cycle of agronomic and horticultural crops with certain imidazolinyl nicotinic acids and derivatives thereof AMERICAN CYANAMID COMPANY (US) 1981-12-16 EP disclosed
US-3935272-A Process for the oxidation of olefine compounds RHONE-POULENC S.A. (FR) 1976-01-27 US disclosed