Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760577 | 0.80 | CA2 (0.46) | CA2KDM4ECYP1A2CYP3A4GAA | |
| SCHEMBL10759314 | 0.76 | CA2 (0.46) | CA2 | |
| SCHEMBL10763085 | 0.76 | CA2 (0.46) | CA2 | |
| SCHEMBL11043589 | 0.72 | CA2 (0.67) | CA2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL10757512 | 0.72 | CA2 (0.48) | CA2 | |
| SCHEMBL10759946 | 0.71 | CA2 (0.57) | CA2 | |
| SCHEMBL10759552 | 0.71 | CA2 (0.54) | CA2KDM4ECYP3A4MAPTMEN1 | |
| SCHEMBL10893526 | 0.69 | CA2 (0.55) | CA2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11043516 | 0.69 | CA2 (0.62) | CA2CYP3A4GAAMAPTKMT2A | |
| SCHEMBL10545135 | 0.68 | CA2 (0.61) | CA2KDM4ECYP3A4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695634-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1987-09-22 | — | — | US | disclosed |
| US-4622406-A | CHEMICAL INTERMEDIATES, TRIMETHYLSILOXY COMPOUNDS | PFIZER INC. (US) | 1986-11-11 | — | — | US | disclosed |
| US-4562267-A | Intermediates of hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1985-12-31 | — | — | US | disclosed |
| US-4423233-A | ALPHA-HYDROXY CARBOXIMIDATE INTERMEDIATES | PFIZER INC. (US) | 1983-12-27 | — | — | US | disclosed |
| US-4381308-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-04-26 | — | — | US | disclosed |
| US-4332952-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1982-06-01 | — | — | US | disclosed |