Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.32 |
| ▸ | KDR | P35968 | 5/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | GRK6 | P43250 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074895 | 0.88 | ALDH1A1 (0.31) | — | |
| SCHEMBL725352 | 0.81 | MPO (0.40) | MPOSMPD1TLR8KDRSLC9A1 | |
| SCHEMBL3774087 | 0.79 | MPO (0.37) | MPOSMPD1TLR8KDRHTR2C | |
| SCHEMBL1074197 | 0.77 | TLR8 (0.33) | MPOTLR8KDRSLC9A1CNR1 | |
| SCHEMBL1074713 | 0.77 | MPO (0.37) | MPOSMPD1TLR8KDRHTR2C | |
| SCHEMBL3781653 | 0.76 | ALDH1A1 (0.36) | MPOTLR8KDRGRK6 | |
| SCHEMBL692560 | 0.74 | MPO (0.40) | MPOTLR8SLC9A1 | |
| SCHEMBL1073396 | 0.72 | TLR8 (0.31) | TLR8CNR1CNR2 | |
| SCHEMBL1076188 | 0.71 | HTR2C (0.38) | MPOSMPD1TLR8KDRHTR2C | |
| SCHEMBL1075354 | 0.68 | GRK6 (0.34) | MPOTLR8HTR2CSLC6A4SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | claimed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | claimed |