Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456197 | 0.83 | MEN1 (0.48) | SOAT1ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL27889242 | 0.81 | MEN1 (0.47) | SOAT1ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL30440649 | 0.81 | MEN1 (0.47) | SOAT1ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL8306724 | 0.81 | MEN1 (0.47) | SOAT1ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL27452723 | 0.77 | SOAT1 (0.61) | SOAT1ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL10980811 | 0.75 | FFAR3 (0.32) | ALDH1A1CYP2C19TSHR | |
| SCHEMBL16222789 | 0.74 | SOAT1 (0.42) | SOAT1ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL8370831 | 0.74 | SOAT1 (0.64) | SOAT1ALDH1A1LMNACYP1A2MEN1 | |
| SCHEMBL11598031 | 0.73 | ALDH1A1 (0.31) | ALDH1A1CYP1A2MEN1KMT2ATHRB | |
| SCHEMBL16569031 | 0.73 | PTPN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4672071-A | Antihypertensive dihydropyridine compositions, optical isomers and intermediates | SYNTEX (U.S.A.) INC. (US) | 1987-06-09 | — | — | US | disclosed |
| US-4595690-A | Hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1986-06-17 | — | — | US | disclosed |