Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10854328 | 0.90 | CDK2 (0.52) | CDK2FLT4HTTL3MBTL1RAB9A | |
| SCHEMBL10753478 | 0.85 | CDK2 (0.52) | CDK2FLT4L3MBTL1RAB9ANPC1 | |
| SCHEMBL10758037 | 0.84 | MDM2 (0.46) | HTTL3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL10756947 | 0.83 | CDK2 (0.57) | CDK2FLT4L3MBTL1RAB9ANPC1 | |
| SCHEMBL10754412 | 0.82 | RAB9A (0.50) | CDK2FLT4HTTL3MBTL1RAB9A | |
| SCHEMBL10756618 | 0.81 | RAB9A (0.54) | CDK2FLT4HTTRAB9ANPC1 | |
| SCHEMBL10756151 | 0.80 | CDK2 (0.64) | CDK2FLT4HTTRAB9ANPC1 | |
| SCHEMBL10757666 | 0.80 | NAMPT (0.57) | HTTL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL10760173 | 0.80 | CDK2 (0.49) | CDK2FLT4HTTL3MBTL1RAB9A | |
| SCHEMBL10758782 | 0.77 | RAB9A (0.50) | CDK2FLT4HTTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707478-A | ANTIPROTOZOA AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |