Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852311 | 0.90 | CDK2 (0.52) | RAB9ANPC1MEN1KMT2ACDK2 | |
| SCHEMBL10753478 | 0.85 | CDK2 (0.52) | RAB9ANPC1MEN1KMT2ACDK2 | |
| SCHEMBL10756947 | 0.83 | CDK2 (0.57) | RAB9ANPC1MEN1KMT2ACDK2 | |
| SCHEMBL10757932 | 0.82 | CDK2 (0.49) | RAB9ANPC1MEN1KMT2ACDK2 | |
| SCHEMBL10756618 | 0.81 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2ACDK2 | |
| SCHEMBL10756151 | 0.80 | CDK2 (0.64) | RAB9ANPC1MEN1KMT2ACDK2 | |
| SCHEMBL10757666 | 0.80 | NAMPT (0.57) | RAB9ANPC1MEN1KMT2AHTT | |
| SCHEMBL10760173 | 0.80 | CDK2 (0.49) | RAB9ANPC1MEN1KMT2ACDK2 | |
| SCHEMBL10760214 | 0.79 | KDM4E (0.49) | RAB9ANPC1MEN1KMT2AFPR2 | |
| SCHEMBL10857089 | 0.77 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2ACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707478-A | ANTIPROTOZOA AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |