Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.60 |
| ▸ | EDNRA | P25101 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756621 | 0.90 | PPARG (0.53) | PPARGEDNRAPPARALMNAKDM4E | |
| SCHEMBL9535567 | 0.89 | PPARG (0.48) | PPARGEDNRAPPARAMAPTLMNA | |
| SCHEMBL9144495 | 0.87 | KDM4E (0.58) | PPARGEDNRAPPARAMAPTKDM4E | |
| SCHEMBL9536815 | 0.81 | MAPK8 (0.51) | PPARGPPARAMAPTLMNAKDM4E | |
| SCHEMBL11038273 | 0.81 | EDNRA (0.57) | PPARGEDNRAPPARAMAPTLMNA | |
| SCHEMBL10412007 | 0.80 | PPARG (0.55) | PPARGEDNRAPPARALMNAKDM4E | |
| SCHEMBL7111400 | 0.80 | EDNRA (0.56) | PPARGEDNRAPPARAMAPTLMNA | |
| Hydrochloric Acid SCHEMBL10462662 | 0.79 | PPARG (0.54) | PPARGEDNRAPPARALMNAKDM4E | |
| SCHEMBL9535097 | 0.78 | PPARG (0.40) | PPARGEDNRAMAPTLMNA | |
| SCHEMBL9141602 | 0.78 | KDM4E (0.53) | PPARGEDNRAMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675332-A | Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0186367-A2 | Acidic indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |