Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SI | P14410 | 4/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11874900 | 0.89 | TDP1 (0.49) | BCHEACHEMGAMGAASI | |
| SCHEMBL11871214 | 0.89 | GAA (0.49) | BCHEACHEMGAMGAASI | |
| SCHEMBL11873339 | 0.85 | ALDH1A1 (0.48) | BCHEACHEGAAALDH1A1KDM4E | |
| SCHEMBL11553308 | 0.82 | ALDH1A1 (0.48) | BCHEACHEGAAALDH1A1KDM4E | |
| SCHEMBL6169396 | 0.82 | MAPK14 (0.54) | KDM4EHPGDSMN1; SMN2 | |
| Bromide SCHEMBL10013030 | 0.82 | HPGD (0.56) | ALDH1A1KDM4EMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL11873336 | 0.81 | ALDH1A1 (0.51) | GAAALDH1A1KDM4ENPSR1MAPK1 | |
| SCHEMBL2475314 | 0.81 | BCHE (0.67) | BCHEACHEMGAMGAASI | |
| SCHEMBL2173277 | 0.79 | BCHE (0.65) | BCHEACHEMGAMGAASI | |
| SCHEMBL12176214 | 0.78 | BCHE (0.51) | BCHEACHEMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4654358-A | 1,4,5-triphenylimidazol-2-yl mercapto alkanoic acids, useful against inflammation and diseases responding to lipid lowering | A. NATTERMANN & CIE GMBH (DE) | 1987-03-31 | — | — | US | disclosed |
| US-3993661-A | Quinone methide photograhpic reagent precursors | POLAROID CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |