Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759394 | 1.00 | KMT2A (0.52) | KMT2AMEN1MAPTLMNARECQL | |
| SCHEMBL3468039 | 0.83 | HPGD (0.55) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL3468037 | 0.83 | HPGD (0.55) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL3468034 | 0.83 | HPGD (0.55) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL10755753 | 0.83 | MAPT (0.53) | KMT2AMEN1MAPTLMNARECQL | |
| SCHEMBL10755749 | 0.83 | MAPT (0.53) | KMT2AMEN1MAPTLMNARECQL | |
| SCHEMBL10757702 | 0.76 | KMT2A (0.44) | KMT2AMEN1MAPTLMNARECQL | |
| SCHEMBL10757707 | 0.76 | KMT2A (0.44) | KMT2AMEN1MAPTLMNARECQL | |
| SCHEMBL700297 | 0.72 | TSHR (0.60) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL7690121 | 0.69 | GAA (0.59) | KMT2AMEN1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668686-A | 1,3-DIHYDRO-2H-IMIDAZO/4,5-B/QUINOLINE-2-ONES | BRISTOL-MYERS COMPANY (US) | 1987-05-26 | — | — | US | disclosed |