Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468037 | 1.00 | HPGD (0.55) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3468039 | 1.00 | HPGD (0.55) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10759394 | 0.83 | KMT2A (0.52) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10759390 | 0.83 | KMT2A (0.52) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7690121 | 0.80 | GAA (0.59) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7690119 | 0.80 | GAA (0.59) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15305605 | 0.74 | MEN1 (0.67) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10750988 | 0.72 | GSK3B (0.68) | HPGDGAAMEN1KMT2AMAPT | |
| SCHEMBL10750983 | 0.72 | GSK3B (0.68) | HPGDGAAMEN1KMT2AMAPT | |
| SCHEMBL16788878 | 0.71 | GSK3B (0.57) | HPGDGAAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2002090360-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-14 | — | — | WO | disclosed |