Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549647 | 0.79 | POLB (0.51) | POLBNPC1PIN1KDM4EALDH1A1 | |
| SCHEMBL11673765 | 0.78 | POLB (0.50) | POLBNPC1PIN1KDM4EALDH1A1 | |
| SCHEMBL10764119 | 0.77 | POLB (0.49) | POLBNPC1PIN1KDM4EALDH1A1 | |
| SCHEMBL10366787 | 0.77 | POLB (0.56) | POLBNPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL11561878 | 0.74 | POLB (0.56) | POLBNPC1KDM4ESMN1; SMN2CA12 | |
| SCHEMBL11555994 | 0.74 | GAA (0.54) | POLBNPC1KDM4EALDH1A1CA12 | |
| SCHEMBL1310721 | 0.74 | PTPN1 (0.55) | POLBNPC1PIN1KDM4EALDH1A1 | |
| SCHEMBL11355089 | 0.73 | KDM1A (0.46) | POLBNPC1PIN1ALDH1A1GSK3B | |
| SCHEMBL11355243 | 0.73 | KDM1A (0.46) | POLBNPC1PIN1ALDH1A1GSK3B | |
| SCHEMBL10014193 | 0.73 | PIN1 (0.61) | POLBNPC1PIN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675320-A | INHIBIT GROWTH OF MICROORGANISMS | RIKER LABORATORIES, INC. (US) | 1987-06-23 | — | — | US | disclosed |
| US-4526896-A | Microbiocides | RIKER LABORATORIES, INC. (US) | 1985-07-02 | — | — | US | disclosed |