Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673765 | 0.86 | POLB (0.50) | POLBNPC1PIN1KDM4EMAPT | |
| SCHEMBL11561878 | 0.85 | POLB (0.56) | POLBNPC1KDM4EMAPTTDP1 | |
| SCHEMBL11550083 | 0.85 | POLB (0.44) | POLBNPC1PSMB8GSK3BMEN1 | |
| SCHEMBL10366787 | 0.82 | POLB (0.56) | POLBNPC1KDM4EMAPTTDP1 | |
| SCHEMBL11555994 | 0.80 | GAA (0.54) | POLBNPC1KDM4EMAPTTDP1 | |
| SCHEMBL10759496 | 0.79 | POLB (0.46) | POLBNPC1PIN1KDM4EMAPT | |
| SCHEMBL11739975 | 0.77 | NPC1 (0.62) | POLBNPC1PIN1KDM4EMAPT | |
| SCHEMBL1310721 | 0.76 | PTPN1 (0.55) | POLBNPC1PIN1KDM4EALDH1A1 | |
| SCHEMBL11351034 | 0.76 | ABCC4 (0.57) | POLBNPC1KDM4EMAPTTDP1 | |
| SCHEMBL10014193 | 0.75 | PIN1 (0.61) | POLBNPC1PIN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153716-A | BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1979-05-08 | — | — | US | disclosed |